Šwp˜_•¶


R.M. Casco-Robles, A. Watanabe, K. Eto, K. Takeshima, S. Obata, T. Kinoshita, T. Ariizumi, K. Nakatani, T. Nakada, P.A. Tsonis, M.M. Casco-Robles, K. Sakurai, K. Yahata, F. Maruo, F. Toyama, C. Chiba. 2018. Novel erythrocyte clumps revealed by an orphan gene Newtic1 in circulating blood and regenerating limbs of the adult newt. Sci. Rep. 8: 7455. doi:10.1038/s41598-018-25867-x


S. Kon, T. Sato, D. Endo, T. Takahashi, A. Takaku, Y. Nakauchi, F. Toyama, V. B. Meyer-Rochow, E. Takayama-Watanabe, A.Watanabe. 2017. Sperm storage influences the potential for spontaneous acrosome reaction of the sperm in the newt Cynops pyrrhogaster. Mol. Reprod. Dev. 84: 1314-1322. DOI: 10.1002/mrd.22932.


T. Sato, M. Yokoe, D. Endo, M. Morita, F. Toyama, Y. Kawamura, Y. Nakauchi, E. Takayama-Watanabe, A. Watanabe. 2017. Sperm motility initiating substance may be insufficient to induce forward motility of Cynops ensicauda sperm. Mol. Reprod. Dev. 84: 686-692.


M. Yokoe, E. Takayama-Watanabe, Y. Saito, M. Kutsuzawa, K. Fujita, H. Ochi, Y. Nakauchi, A. Watanabe. 2016. A novel cysteine knot protein for enhancing sperm motility that might facilitate the evolution of internal fertilization in amphibians. PLOS ONE 11: e0160445.


E. Takayama-Watanabe,  H. Ochiai,  S. Tanino,  A. Watanabe.  2015. Contribution of different Ca2+ channels to the acrosome reaction-mediated initiation of sperm motility in the newt Cynops pyrrhogaster. Zygote 23:  342-351.


A. Watanabe,  E. Takayama-Watanabe.  2014.  In silico identification of the genes for sperm-egg interaction in the internal fertilization of the newt Cynops pyrrhogaster. Int. J. Dev. Biol.  58: 873-879.


M. Yokoe,  M.  Sano,  H.  Shibata,  D.  Shibata,  E.  Takayama-Watanabe,  K.  Inaba,  A.  Watanabe. 2014. 
Sperm proteases that may be involved in the initiation of sperm motility in the newt, Cynops pyrrhogaster.  Int.  J.  Mol.  Sci.  15: 15210-15224.


E. Takayama-Watanabe,  T. Takahashi,  M. Yokoe,  A. Watanabe.  2014.  Acrosome reaction-mediated motility initiation that is critical for the internal fertilization of urodele amphibians. In Sexual reproduction in animals and plants.  H.  Sawada, N.  Inoue, M.  Iwano (eds) Springer, Tokyo, Japan, pp. 97-103.


T. Takahashi,  M. Kutsuzawa,  K. Shiba,  E. Takayama-Watanabe,  K. Inaba,  A. Watanabe. 2013. Distinct Ca2+ channels maintain a high motility state of the sperm that may be needed for penetration of egg jelly of the newt, Cynops pyrrhogaster. Develop. Growth Differ.  55: 657-667.


E. Takayama-Watanabe,  C. Campanella,  H. Kubo A.  Watanabe. 2012. Sperm motility initiation by egg jelly of the anuran, Discoglossus pictus may be mediated by sperm motility-initiating substance of the internally-fertilizing newt, Cynops pyrrhogaster. Zygote 20: 417-422.


‘ì—mˆêA’†“à—S“ñA¬—Ñ–qlA@Œ´OKA‹S•ˆê•vA“n•Ó–¾•F@2011. ƒJƒWƒJ—Þ‚É‚¨‚¯‚éˆÙŒ^¸Žq‚Ì•ª‰»‹@\‚Æ‹@”\@In: ƒJƒWƒJ—ނ̐¢ŠE@~“K‰ž‚Ɛi‰»~ Œã“¡WA@Œ´OKA–î•”‰q•Ò@pp.133-143@“ŒŠC‘åŠwo”ʼnï


Y. Nakauchi,  Y. Hayakawa,  M. Fujinoki,  O.Yamamura,  M. Kobayashi,  A. Watanabe. 2011. Characterization of an alternative chromatin remodeling to parasperm in a cottid fish, Hemilepidotus gilberti. Zool. Sci. 28: 438-443.


A. Watanabe,  E. Takayama-Watanabe,  C. A. Vines,  G. N. Cherr. 2011. Sperm motility-initiating substance in newt egg-jelly induces differential initiation of sperm motility based on sperm intracellular calcium levels. Develop. Growth Differ. 53: 9-17.

M. Ohta,  H. Kubo,  Y. Nakauchi  A. Watanabe. 2010. Sperm motility-initiating activity in the egg jelly of the externally-fertilizing urodele amphibian, Hynobius lichenatus. Zool. Sci. 27: 875-879.
 
T. Watanabe,  H. Kubo,  S. Takeshima,  M. Nakagawa,  M. Ohta,  S. Kamimura,  E. Takayama-Watanabe,  A. Watanabe,  K. Onitake. 2010. Identification of the sperm motility-initiating substance in the newt, Cynops pyrrhogaster, and its possible relation with the acrosome reaction during internal fertilization. Int. J. Dev. Biol. 54: 591-597.

Y. Iwasaki,  K. Ohkawa,  H. Sadakata,  A. Kashiwadate,  E. Takayama-Watanabe,  K. Onitake,  A. Watanabe. 2009. Two states of active spermatogenesis switch between reproductive and non-reproductive seasons in the testes of the medaka, Oryzias latipes. Develop. Growth Differ. 51: 521-532.


A. Watanabe. 2009 Spermatogenesis, In vitro spermatogenesis from primary spermatocytes. In
  MedakaBiology, Management, and Experimental Protocols. M. Kinoshita, K. Murata, M. Tanaka (Eds.).  Blackwell publishing Ltd pp. 74-75, 350-353.

A. Watanabe,  K. Fukutomi,  H. Kubo,  M. Ohta,  E. Takayama-Watanabe,  K. Onitake. 2009. Identification of egg-jelly substances triggering sperm acrosome reaction in the newt, Cynops pyrrhogaster. Mol. Reprod. Dev. 76: 399-406.


Y. Hayakawa,  E. Takayama-Watanabe,  A. Watanabe,  M. Kobayashi,  H. Munehara,  K. Onitake. 2007. Partial formation of sperm dimorphism from spermatocytes of the cottoid fish, Hemilepidotus gilberti in cell culture. Zygote 15: 285-293.


W. Hiyoshi,  T. Sasaki,  E. Takayama-Watanabe,  H. Takai,  A. Watanabe,  K. Onitake. 2007. Egg-jelly of the newt, Cynops pyrrhogaster contains a factor essential for sperm binding to the vitelline envelope. J. Exp. Zool. 307A: 301-311.


A. Watanabe,
  K. Onitake. 2007. The Regulation of Spermatogenesis in Fish: Recent Cellular and Molecular Approaches In: "Fish Spermatology. " eds. by S.M.H. Alavi, J.J. Cosson, K. Coward, & Gh. Rafiee, Oxford, Alpha Science Ltd@Publications, pp. 141-160.


Y. Hayakawa,  M. Kobayashi,  H. Munehara,  A. Watanabe,  K. Onitake. 2007. Spermatogenesis involving parasperm production in the marine cottoid fish, Hemilepidotus gilberti. The Raffles Bulletin of Zoology, Sup 14: 29-35.


S. Takahashi,  H. Nakazawa,  A. Watanabe,  K. Onitake,
  2006. The outermost layer of egg-jelly is crucial to successful fertilization in the newt, Cynops pyrrhogaster. J. Exp. Zool. 305A: 1010-1017.


T. Sasaki,  A. Watanabe,  E. Takayama-Watanabe,  M. Suzuki,  H. Abe,  K. Onitake. 2005. Ordered progress of spermiogenesis to the fertilizable sperm of the medaka fish, Oryzias latipes, in cell culture. Develop. Growth Differ. 47: 87-97.


A. Watanabe,  K. Onitake. 2003. Sperm activation. In "Reproductive biology and phylogeny of urodela." ed. by David M. Sever. Science publisher, Inc. Enfield (NH). USA. pp.425-445.


Y. Makabe-Kobayashi,  E. Kudaira,  A. Watanabe,  K. Onitake. 2003. Newt ZPC molecule, cpZPC, localizes in the inner surface of the egg envelope. Int. J. Dev. Biol. 47: 51-58.


T. Watanabe,  T. Itoh,  A. Watanabe,  K. Onitake. 2003. Characteristics of sperm motility induced on the egg-jelly in the internal fertilization of the newt, Cynops pyrrhogaster. Zool. Sci. 20: 345-352.


A. Watanabe,  K. Onitake. 2002. Urodela egg-coat as the apparatus for the internal fertilization. Zool. Sci. 19: 1341-1347.


T. Sasaki,  S. Kamimura,  H. Takai,  A. Watanabe,  K. Onitake. 2002. The activity for the induction of sperm acrosome reaction localises in the outer layers and exists in the high molecular weight components of egg-jelly of the newt, Cynops pyrrhogaster. Zygote 10: 1-9.


T. Itoh,  S. Kamimura,  A. Watanabe,  K. Onitake. 2002. Egg-jelly structure promotes efficiency of internal fertilization in the newt, Cynops pyrrhogaster. J. Exp. Zool. 292: 314-322.


M. Okimura,  A. Watanabe,  K. Onitake. 2001. Organization of carbohydrate components in the egg-jelly layers of the newt, Cynops pyrrhogaster. Zool. Sci. 18: 909-918.


K. Onitake,  H. Takai,  M. Ukita,  J. Mizuno,  T. Sasaki ,  A. Watanabe. 2000. Significance of egg-jelly substances in the internal fertilization of the newt, Cynops pyrrhogaster. Comp. Biochem. Physiol. 126: 121-128.


J. Mizuno,  A. Watanabe,  K. Onitake. 1999. Initiation of sperm motility in the newt, Cynops pyrrhogaster, is induced by a heat-stable component of egg-jelly. Zygote. 7: 329-334.


M. Ukita,  T. Itoh,  T. Watanabe,  A. Watanabe,  K. Onitake. 1999. Substances for the initiation of sperm motility in egg-jelly of the Japanese newt, Cynops pyrrhogaster. Zool. Sci. 16: 793-802.


S. Nakai,  A. Watanabe,  K. Onitake. 1999. Sperm surface heparin/heparan sulfate is responsible for sperm binding to the uterine envelope in the newt, Cynops pyrrhogaster. Develop. Growth Differ. 41: 101-107.


A. Watanabe,  E. Kobayashi,  T. Ogawa,  K. Onitake. 1998. Fibroblast growth factor may regulate the initiation of oocyte growth in the developing ovary of the medaka, Oryzias latipes. Zool. Sci. 15: 531-536.


A. Saiki,  M. Tamura,  M. Matsumoto,  J. Katowgi,  A. Watanabe,  K. Onitake. 1997. Establishment of in vitro spermatogenesis from spermatocytes in the medaka Oryzias latipes. Develop. Growth Differ. 39: 337-344.


A. Watanabe,  N. Hatakeyama,  A. Yasuoka,  K. Onitake. 1997. Distributions of fibroblast growth factor and the mRNA for its receptor, MFR1, in the developing testis of the medaka, Oryzias latipes. J. Exp. Zool. 279: 177-184.


A. Watanabe,  K. Onitake.1995. Changes in the distribution of fibroblast growth factor in the teleostean testis during spermatogenesis. J. Exp. Zool. 272: 475-483.


A. Watanabe,  H. Ide. 1993. Basic FGF maintains some characteristics of the progress zone of chick limb bud in cell culture. Dev. Biol. 159: 223-231.


A. Watanabe,  K. Ohsugi,  H. Ide. 1993. Formation of distal structures from stumps of chick wing buds at stage 24-25 following the grafting of quail tissue from X-irradiated distal limb buds. J. Exp. Zool. 267: 447-453.

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”ŽŽm˜_•¶
2003
”N
“n•Ó@r•F@@@‘Ì“àŽó
¸‚ðs‚¤ƒAƒJƒnƒ‰ƒCƒ‚ƒŠ¸Žq‰^“®ŠJŽnˆöŽq‚Ì’Tõ‚Æ‚»‚Ì“Á’¥‚̉ðÍ

 

2004”N
ŽRà_@—R”ü@@@ƒJƒCƒR—‘‚É‚¨‚¯‚é—‘‰©ƒ^ƒ“ƒpƒNŽ¿•ª‰ð‚Ì’²ß‹@\‚ÉŠÖ‚·‚錤‹†@i˜_•¶”ŽŽmj

 

2005”N
²X–؁@—²L@@×–E”|—{Œn‚ð—p‚¢‚½ƒƒ_ƒJ¸ŽqŠ®¬‚É‚¨‚¯‚éƒJƒXƒp[ƒ[Šˆ«‚Ì–ðŠ„‚Ì‰ðÍ


CŽm˜_•¶
1990
”N@C—¹
Ö–؁@“ÄŽj@@”|—{‰º‚É‚¨‚¯‚郁ƒ_ƒJ¸•ê×–E‚©‚ç‚̐¸ŽqŒ`¬‚ɂ‚¢‚Ä
‚–ì@­‹`@@ƒƒ_ƒJ—‘‚É‚¨‚¯‚é—‘–å‚Ɛ¸Žq‚Ì‘ŠŒÝì—p‚ɂ‚¢‚Ä

 

1992”N@C—¹
ŽRà_@—R”ü@@ƒCƒ‚ƒŠ‚̑̍o“à—‘—A‘—‚ÌŒ¤‹†
‘«—§@—E”Ž@@ƒCƒ‚ƒŠ‘̍o—‘—‘–Œ‚ÌŽq‹{—‘—“–Œ‚ւ̕ω»‹@\‚È‚ç‚тɎ󐸂ɔº‚¤—‘–Œ•Ï‰»‚ɂ‚¢‚Ä
‚ˆä@—T”V@@ƒCƒ‚ƒŠ(Cynops pyrrhogaster)‚Ì—‘ƒWƒF
ƒŠ[‘w‚ÉŠÜ‚Ü‚ê‚鐸Žqæ‘Ì”½‰ž—U‹N•¨Ž¿‚̉ðÍ

 

1993”N@C—¹
¼–{@^²”ü@ŠíŠ¯”|—{‰º‚É‚¨‚¯‚郁ƒ_ƒJ¸‘ƒ’f•Ð“à‚ł̐¸ŽqŒ`¬

 

1994”N C—¹
—é–؁@’l@@ƒCƒ‚ƒŠ—‘‚Ì—‘–ŒŒ`¬‚Æ‚»‚ÌŠ®¬‰ß’ö‚ɂ‚¢‚Ä‚ÌŒ¤‹†
¼“c@K‘ã@@ƒCƒ‚ƒŠ—‘ƒWƒFƒŠ[‘w’†‚ÉŠÜ‚Ü‚ê‚鐸Žqæ‘Ì”½‰ž—U‹N•¨Ž¿‚̖ƉuŠw“IŒ¤‹†
—é–؁@½@@@×–E”|—{Œn‚É‚¨‚¯‚郁ƒ_ƒJ¸ŽqŒ`¬‰ß’ö‚Ì“dŽqŒ°”÷‹¾“IŠÏŽ@

 

1995”N@C—¹
ã‘º@‚³‚¨‚è@ƒAƒJƒnƒ‰ƒCƒ‚ƒŠ—‘ƒWƒFƒŠ[‘w‚ª‚à‚Šɂ₩‚È‘½¶‹‘”Û‹@\‚̉ðÍ
•‚“c@¹•F@@ƒAƒJƒnƒ‰ƒCƒ‚ƒŠ—‘ƒWƒFƒŠ[‘w’†‚ÉŠÜ‚Ü‚ê‚鐸Žq‰^“®ŠJŽnˆöŽq‚̉ðÍ
“c‘º
@Ÿ@@@ƒƒ_ƒJƒvƒƒ^ƒ~ƒ“ˆâ“`Žq‚̃Nƒ[ƒjƒ“ƒO‚Æ‚»‚̐¸ŽqŒ`¬‰ß’ö‚É‚¨‚¯‚é”­Œ»

 

1996”N@C—¹
Ä“¡@˜NŽq@@ƒAƒJƒnƒ‰ƒCƒ‚ƒŠ—‘—‘–ŒŒ`¬‰ß’ö‚Ì’´”÷Œ`‘ÔŠw“IŒ¤‹†
’†‹@‘@@@ƒAƒJƒnƒ‰ƒCƒ‚ƒŠ—‘—‘–Œ‚̎󐸂ɂ¨‚¯‚é‹@”\‚̉ðÍ
²X–؁@—²s@ƒAƒJƒnƒ‰ƒCƒ‚ƒŠ‚̐¸Žqæ‘Ì”½‰ž—U‹N‚ÉŠÖ‚í‚éˆöŽq‚̉ðÍ

 

1997”N@C—¹
ˆÉ“¡@“¿Žq@@ƒAƒJƒnƒ‰ƒCƒ‚ƒŠ—‘ƒWƒFƒŠ[‘wƒ‚ƒfƒ‹‚ð—p‚¢‚½¸Žq‚̎󐸃VƒXƒeƒ€‚̉ðÍ@
@@@@@@@@-¸Žq‚̉^“®’²ßƒVƒXƒeƒ€‚ɂ‚¢‚Ä-
”©ŽR@“TŽq@@ƒƒ_ƒJ¸‘ƒ‚É‚¨‚¯‚é‘@ˆÛ‰è×–E‘BˆöŽq‹y‚шâ“`Žq‚Ì”­Œ»•”ˆæ‚̉ðÍ

 

1998”N@C—¹
’r“c@KO@@ƒƒ_ƒJ¸‘ƒ“à‚É‚¨‚¯‚鐸Œ´×–E‚ÆFGF‚Ì”­Œ»—lŽ®‚ÉŠÖ‚·‚錤‹†
¬ì@‘ñ@@@ƒƒ_ƒJ—‘‘ƒ‚Ì”­¶‚É”º‚¤FGF‚Ì”­Œ»‚̕ω»‚ÉŠÖ‚·‚錤‹†
…–ì@ƒˆê@@ƒAƒJƒnƒ‰ƒCƒ‚ƒŠ‚̐¸Žq‰^“®’²ß‚ÉŠÖ‚í‚éƒ^ƒ“ƒpƒNŽ¿ˆöŽq‚̉ðÍ

 

1999”N@C—¹
ŽR“c@
“N–ç@@‰º“™Ò’Å“®•¨‚̏¬—tŒ^¸‘ƒ‚É‚¨‚¯‚éFGF‚Ì”­Œ»‚ÉŠÖ‚·‚錤‹†
‰““¡@„@@@ƒƒ_ƒJ¸‘ƒ‚É‚¨‚¢‚ÄFGF‚ð”­Œ»‚·‚鐸Œ´×–E‚Ì“Á«‚ÉŠÖ‚·‚錤‹†
‰«‘º@¹•F@@ƒŒƒNƒ`ƒ“‚ð—p‚¢‚½ƒCƒ‚ƒŠ—‘ƒWƒFƒŠ[‘w’†‚Ì“œ½‚̋Ǎ݂Ɋւ·‚錤‹†
^•Ç@—zŽq@@ƒCƒ‚ƒŠZP3ˆâ“`Žq‚Ì’P—£‚Æ”­Œ»‚̉ðÍ

 

2000”N@C—¹
‘åì@ŒbŽq@@ŠíŠ¯”|—{Œn‚ð—p‚¢‚½ƒƒ_ƒJ¸ŽqŒ`¬‚̐is’²ß‚ÉŠÖ‚·‚錤‹†
“n•Ó@r•F@@ƒAƒJƒnƒ‰ƒCƒ‚ƒŠ¸Žq‚̉^“®’²ß‚É‚¨‚¯‚éƒ^ƒ“ƒpƒNŽ¿ˆöŽq‚ƃCƒIƒ“‚Ì–ðŠ„‚Ì‰ðÍ

 

2001”N@C—¹
‰ª‘º@r–ç@@
ƒCƒ‚ƒŠZP3ˆâ“`Žq‚̐¶B‘ƒ‚É‚¨‚¯‚é”­Œ»‚ÉŠÖ‚·‚錤‹†
H•½@‰xŽq@@ƒCƒ‚ƒŠZP3
ƒyƒvƒ`ƒhR‘Ì‚ð—p‚¢‚½—‘–ŒŒ`¬‰ß’ö‚̖ƉuŠw“IŒ¤‹†
²X–؁@—²L@×–E”|—{‰º‚Å•ª‰»‚µ‚½ƒƒ_ƒJ‚̎󐸔\‚ÌŒŸØ
‰Á“¡@D”ü@@ƒƒ_ƒJ—‘‘ƒ‚Ì”­¶‚É‚¨‚¯‚éFGF‚Ì•ª•z‚̕ω»‚ÉŠÖ‚·‚錤‹†

 

2002”N@C—¹
’å•û@‹vl@@ƒƒ_ƒJ¸ŽqŒ`¬‚ÌŽü”N•Ï‰»‚Æ‚»‚Ì’²®‹@\‚ÉŠÖ‚·‚錤‹†
“ú‹g@Â@@@ƒŒƒNƒ`ƒ“‚ð—p‚¢‚½ƒCƒ‚ƒŠ¸Žq‚̐æ‘Ì”½‰ž—U‹N‚Æ—‘
–Œ‚ւ̐ڒ…‹@\‚̉ðÍ

 

2006”N@C—¹
’|“‡@LÆ@@ƒEƒGƒXƒ^ƒ“ƒuƒƒeƒBƒ“ƒO–@‚ð—p‚¢‚½ƒAƒJƒnƒ‰ƒCƒ‚ƒŠ¸Žq‰^“®ŠJŽnˆöŽq‚̉ðÍ
•Ÿ•x@
ŒhŽq@@ƒ‚ƒmƒNƒ[ƒiƒ‹R‘Ì‚ð—p‚¢‚½ƒCƒ‚ƒŠ¸Žqæ‘Ì”½‰ž—U‹N•¨Ž¿‚Ì“¯’è

 

2009”N@C—¹
‹g‰ª@‹MŽu@@ƒƒ_ƒJ¸ŽqŒ`¬×–E‚É‚¨‚¯‚éƒJƒXƒp[ƒ[Šˆ«‚Ì”­Œ»‚ÉŠÖ‚·‚錤‹†

 

2010”N@C—¹

‘¾“c@^“Þ”ü@@ƒAƒJƒnƒ‰ƒCƒ‚ƒŠæ‘Ì”½‰ž—U‹N•¨Ž¿‚̐¶—Šˆ«‚ÉŠÖ—^‚·‚é“œ½‚̉ðÍ

 

2011”N@C—¹

—Ž‡@Ll@@ƒCƒ‚ƒŠ—‘—¸Žq‘ŠŒÝì—p‚̃Jƒ‹ƒVƒEƒ€ƒCƒIƒ“ƒ`ƒƒƒlƒ‹ˆË‘¶ «‚ÉŠÖ‚·‚é–ò—Šw“IŒ¤‹†
ŒB‘ò@Œb@@@ƒCƒ‚ƒŠ—‘ƒWƒFƒŠ[‘w‚É‘¶Ý‚·‚éV‹K¸Žq‰^“®ŠJŽnˆöŽq‚̈â“`Žq‚Ì“¯’è

 

2013”N@C—¹

Vˆä@•¶i@@ƒƒ_ƒJ¶B×–E‚̃Aƒ|ƒg[ƒVƒX‚É‚æ‚鐸ŽqŒ`¬Šˆ«‚Ì’²ß‚ÉŠÖ‚·‚錤‹†

 

2014”N

‚‹´@’qŒb@@ƒCƒ‚ƒŠ¸Žq‚Ì•”ˆæ“ÁˆÙ“I‚ȉ^“®Šˆ«‰»‹@\‚É‚¨‚¯‚éƒTƒCƒNƒŠƒbƒNƒkƒNƒŒƒIƒ`ƒh‚Ì–ðŠ„
‰¡]@”ü—¢@@¸
q‰^“®ŠJŽnˆöŽq‚ÌŠˆ«ƒyƒvƒ`ƒh‚ð—p‚¢‚½—¼¶—ސ¸Žq‚̉^“®ŠJŽn^Šˆ«‰»‹@\‚Ì”äŠr‰ðÍ

 

2015”N

—L‘º@Œ’Žu@ƒAƒ‹ƒfƒqƒhƒŠƒ_ƒNƒ^[ƒ[KOƒ}ƒEƒX¸Žq‚Ì‘å‚«‚­‹ü‹È‚·‚é•Ú–щ^“®‚ÉŠÖ‚·‚錤‹†

 

2017 ”N

‹ß@a”V‰î@ƒIƒX‚É‚æ‚é’™¸‚ªƒAƒJƒnƒ‰ƒCƒ‚ƒŠ¸Žq‚ÌŽ©”­“Iæ‘Ì”½‰ž—}§‹@\‚É‹y‚Ú‚·‰e‹¿

 

2018 ”N

…ŒË@T–ç@ƒAƒJƒnƒ‰ƒCƒ‚ƒŠ—‘ƒWƒFƒŠ[‘w‚É‚¨‚¯‚éSMIS‚̋Ǎ݌`¬‚ÉŠÖ‚·‚錤‹†

²“¡@‘½Œb@—¼¶—ސ¸Žq‚̉^“®’²ß‚Ì‘½—l‰»‚ÉŠÖ‚í‚é×–EM†“`’BŒn‚̕ω»‚ÉŠÖ‚·‚錤‹†

 


‘²‹Æ˜_•¶
1987
”N
X@˜a—²@@@ƒCƒ‚ƒŠ—‘–Œ‚̖ƉuŠw“I‰ðÍ

 

1988”N
”óŒû@‰„’j@@
ƒ‚ƒmƒNƒ[ƒiƒ‹R‘Ì–@‚ð—p‚¢‚½ƒƒ_ƒJã󕪉»ƒ}[ƒJ[‚ÌŒŸo‚ÌŽŽ‚Ý
‹g“c@’¼Žj@@ƒCƒ‚ƒŠ—‘–Œ‚ɑ΂·‚郂ƒmƒNƒ[ƒiƒ‹R‘̍쐻‚ÌŽŽ‚݂ƃ|ƒŠƒNƒ[ƒiƒ‹R‘Ì‚É‚æ‚é—‘–ŒŒ`¬‰ß’ö‚ÌŠÏŽ@
¼ŽR@“T]@@ƒCƒ‚ƒŠ—‘‚̐¸ŽqN“ü•”ˆÊ‚ɂ‚¢‚Ä
Ö–؁@“ÄŽj@@ƒƒ_ƒJ¶B‘B”|—{‚ÌŽŽ‚Ý
‚–ì@­‹`@@ƒƒ_ƒJŽó¸—‘Zo•¨‚̐¸Žq‰^“®•Û‘¶”\‚ɂ‚¢‚Ä

 

1989”N
Š‹¼@–«@@@@ƒAƒJƒnƒ‰ƒCƒ‚ƒŠ(Cynops pyrrhogaster)‚É‚¨‚¯‚éŽnŒ´¶B×–E(PGCs)‚Ì‘gD‰»Šw“IŠÏŽ@
²X–؁@Žq@’_ŠÇŠñ¶ð’Ž Hymenolepis microstoma ’Ž—‘‚̃}ƒEƒX’°‘gD“à‚ւ̐N“ü‚ɂ‚¢‚Ä
H“¡@çŒb@@Jones-MoteŒ^’x‰„Œ^‰ß•qÇ‚É‚¨‚¯‚éD’†‹…‚Ì–ðŠ„‚ÉŠÖ‚·‚錤‹†
@@@@@@@`D’†‹…‚ð‘I‘ð“I‚Ɍ͊‰‚³‚¹‚郂ƒmƒNƒ[ƒiƒ‹R‘Ì“Š—^ƒ‰ƒbƒg‚É
¨‚¯‚é‹ÇŠ‚Ö‚Ì’Pj‹…—V‘–‚ðŽw•W‚Æ‚µ‚ā`
ŠÛŽR@_Žq@@ƒAƒJƒnƒ‰ƒCƒ‚ƒŠ‚ÌŠÉ‚â‚©‚È‘½¸‹‘”Û‹@\‚ɂ‚¢‚Ä
›Œ´@—R‹I@@ƒƒ_ƒJ‚Ì—‡—‘‚Ɛ¸Žq‚Ì‘ŠŒÝì—p‚ɂ‚¢‚Ä
‘«—§@—E”Ž@@ƒCƒ‚ƒŠ‚̑̍o—‘—‘–Œ‚ÆŽq‹{—‘—‘–Œ‚Ì”äŠrŒŸ“¢

 

1990”N
ŽRà_@—R”ü@@ƒCƒ‚ƒŠ‚̑̍o“à—‘—A‘—‚ɂ‚¢‚Ä
‚ˆä@—T”V@@ƒCƒ‚ƒŠ¸Žqæ‘Ì”½‰ž‚É‚¨‚¯‚é—‘jelly‘w‚Ì–ðŠ„
‰Á“¡–؁@~@@”|—{‰º‚É‚¨‚¯‚郁ƒ_ƒJiOryzias latipesj‘æˆê¸•ê×–E‚̐¸ŽqŒn¸”\‚ɂ‚¢‚Ä
Æˆä@‰ëŒÈ@@ƒƒ_ƒJ—‘–å’¼‰º•”ˆæ‚͎󐸂ɖ{Ž¿“I‚ÉŠÖ—^‚µ‚Ä‚¢‚é‚©

 

1991”N
Œã“¡@Œ÷@@@ƒƒ_ƒJiOryzias latipesj¸‘ƒ‚©‚ç‰ð—£‚³‚¹‚½¸ŽqŒ`¬×–EŒQ‚ÉŠÜ‚Ü‚ê‚é‘æˆê¸•ê×–Eƒ‰»‚ÌŽŽ‚Ý
¼–{@Œ÷@@@ƒAƒJƒnƒ‰ƒCƒ‚ƒŠ(Cynops pyrrhogaster)¸Žqæ‘Ì”½‰ž—U‹N‰ß’ö‚Ì
‘–¸Œ^“dŽqŒ°”÷‹¾‚É‚æ‚éŠÏŽ@
¼–{@^²”ü@ŠíŠ¯”|—{‚³‚ꂽƒƒ_ƒJiOryzias latipesj¸‘ƒ’f•Ð‚ł̐¸ŽqŒ`¬‚ɂ‚¢‚Ä

 

1992”N
—é–؁@’l@@ƒAƒJƒnƒ‰ƒCƒ‚ƒŠ—‘Œ`¬‰ß’ö‚É‚¨‚¯‚é—‘–ŒŒ`¬‚ɂ‚¢‚Ä
¼“c@K‘ã@@ƒAƒJƒnƒ‰ƒCƒ‚ƒŠæ‘Ì”½‰ž—U‹N•¨Ž¿‚ɑ΂·‚éR‘̂̍쐬‚Æ‚»‚ê‚ð—p‚¢‚ÄŒŸ’肵‚½—A—‘ŠÇ‘gD‚Å‚Ì—U‹N•¨Ž¿‡¬
‰““¡@•üŽq@@ƒƒ_ƒJ¸ŽqŒ`¬‰ß’ö‚É‚¨‚¯‚éƒvƒƒ^ƒ~ƒ“‚̍‡¬‚ɂ‚¢‚Ä

 

1993”N
Ÿ–”@Š²•v@@ƒGƒXƒgƒ‰ƒWƒI[ƒ‹“Š—^‚̃ƒ_ƒJiOryzias latipesj¸ŽqŒ`¬‚É‹y‚Ú‚·‰e‹¿‚ɂ‚¢‚Ä
“c‘º@Ÿ@@@ƒƒ_ƒJiOryzias latipesj¸‘ƒ‚É‚¨‚¯‚écDNAƒ‰ƒCƒuƒ‰ƒŠ[‚̍쐬
ŽO–؁@r•F@@ƒƒ_ƒJiOryzias latipesj‚̐¸Žq×–E•\–ʍRŒ´‚̉ðÍ
•‚“c@¹•F@@ƒAƒJƒnƒ‰ƒCƒ‚ƒŠ(Cynops pyrrhogaster)¸Žq‚̉^“®«‚ɑ΂·‚éŠeŽí‰–—Þ—n‰t‚̉e‹¿
ã‘º@‚³‚¨‚è@—‘ƒWƒFƒŠ[‘w’ʉߒ†‚̃AƒJƒnƒ‰ƒCƒ‚ƒŠ(Cynops pyrrhogaster)¸Žq‚ÌŒ`‘ԕω»‚ɂ‚¢‚Ä
‹´–{@TŽ¡@@ƒAƒJƒnƒ‰ƒCƒ‚ƒŠ(Cynops pyrrhogaster)¸Žq‚ɑ΂·‚éR¸ŽqR‘̂̍쐬‚Æ‚»‚ê‚ð—p‚¢‚½¸Žq•\–ʍRŒ´‚̉ðÍ

 

1994”N
Ž½Œ´@K•v@@ƒƒ_ƒJiOryzias latipesj¸‘ƒ‚Ì’·ŠúŠÔ”|—{–@‚ÌŠm—§‚ÌŽŽ‚Ý
—é–؁@NO@@×–E”|—{‰º‚É‚¨‚¯‚郁ƒ_ƒJ‘æˆê¸•ê×–E‚©‚琸Žq‚Ö‚Ì•ª‰»‰ß’ö‚ÌBrdU•WŽ¯–@‚É‚æ‚é‰ðÍ
Ä“¡@˜NŽq@@ƒAƒJƒnƒ‰ƒCƒ‚ƒŠiCynops pyrrhogasterj—‘‘ƒ‚ÌcDNAƒ‰ƒCƒuƒ‰ƒŠ[‚̍쐬
’†‹@‘@@@ƒAƒJƒnƒ‰ƒCƒ‚ƒŠ‚Å‚Í—‘–ŒŠ®¬‰ß’ö‚ŃrƒgƒƒlƒNƒ`ƒ“—l•¨Ž¿‚ª—A—‘ŠÇã•”‚Å—‘–Œ‚É•t‰Á‚³‚ê‚é
²X–؁@—²s@‹z…‚ð‚³‚¹‚½ƒAƒJƒnƒ‰ƒCƒ‚ƒŠ(Cynops pyrrhogaster)—‘ƒWƒFƒŠ[‘w‚̎󐸂ɂ¨‚¯‚é–ðŠ„‚É‚Â‚¢‚Ä
‚‹´@‘P•F@@ŽnŒ´¶B×–E—R—ˆ‚̍זEŠ”‚𐶐B×–E‚É•ª‰»‚³‚¹
‚éˆöŽq

 

1995”N
‚–ì@³Žk@@ƒƒ_ƒJ¸‘ƒ’f•Ð‚̊튯”|—{‚Æ”|—{‰º‚É‚¨‚¯‚éFGF‚Ì•ª•z‚ɂ‚¢‚Ä
¬—с@Œb”üŽq@ƒƒ_
ƒJ¶B‘ƒ‚Ì”­¶‰ß’ö‚É‚¨‚¯‚éFGFƒ^ƒ“ƒpƒNŽ¿‚Ì•ª•z
”©ŽR@“TŽq@@ƒCƒƒi(Salvelinus leucomaenis)¸ŽqŒ`¬×–E‚̏‰Šú•ª‰»’iŠK‚ð•WŽ¯‚·‚郂ƒmƒNƒ[ƒiƒ‹R‘̂̍쐻
Œã“¡@–FŽ÷@@ƒAƒJƒnƒ‰ƒCƒ‚ƒŠ—A—‘ŠÇ’¼•”‚Ì‘–¸Œ^“dŽqŒ°”÷‹¾‚É‚æ‚éŠÏŽ@
ˆÉ“¡@“¿Žq@@ƒAƒJƒnƒ‰ƒCƒ‚ƒŠiCynops pyrrhogasterj—‘ƒWƒFƒŠ[‘w‚͎󐸎ž‚ɐ¸ŽqˆÚ“®‚Ì‘«ê‚Æ‚È‚é
‚£@ä°@@ŽRŒ`Œ§‚Æ‹{éŒ§‚©‚çÌW‚µ‚½ƒCƒ‚ƒŠW’c‚̈â“`“I•ª‰»

 

1996”N
¬ì@‘ñ@@@ƒƒ_ƒJ(Oryzias latipes)àm–E×–E”|—{Œn‚É‚¨‚¯‚é‘@ˆÛ‰è×–E‘BˆöŽq‹y‚яã”琬’·ˆöŽq‚̍ì—p‚ÉŠÖ‚·‚錤‹†
…–ì@ƒˆê@@ƒAƒJƒnƒ‰ƒCƒ‚ƒŠ(Cynops pyrrhogaster)¸Žq‰^“®ŠJŽnˆöŽq‚Ì‘e¸»
’r“c@KO@@ƒƒ_ƒJ(Oryzias latipes)¸‘ƒ“à‘Ì
×–E‚̍זE”|—{
ŽR“c@“N–ç@@ƒƒ_ƒJiOryzias latipesj¸‘ƒ’f•Ð‚Ì’·ŠúŠÔ”|—{‚ÌŽŽ‚Ý

 

1997”N
‰““¡@„@@@ƒƒ_ƒJ¸Žq‰Šú‰ß’ö‚É“ÁˆÙ“I‚É”­Œ»‚·‚éˆâ“`Žq‚Ì’P—£‚ÌŽŽ‚Ý
‰«‘º@¹•F@@ƒAƒJƒnƒ‰ƒCƒ‚ƒŠ¸Žq‚̐æ‘Ì”½‰ž—U‹N‚ÉŠÖ‚í‚镪Žq‚ɂ‚¢‚Ä‚ÌŒ¤‹†

 

1998”N
‘åì@ŒbŽq@@ŠíŠ¯”|—{Œn‚ð—p‚¢‚½ƒƒ_ƒJ¸‘ƒ‚É‚¨‚¯‚é‘@ˆÛ‰è×–E‘BˆöŽq‚̍ì—p‚̉ðÍ
¬ì@^Œá@@ƒƒ_ƒJ
¸‘ƒ‚É‚¨‚¯‚éƒGƒXƒgƒƒQƒ“‚̍ì—p‚̉ðÍ‚Ì‚½‚߂̊튯”|—{Œn‚̍쐬
”ŠÚ@Œ[Žq@@ƒƒ_ƒJ¸‘ƒ‚É‚¨‚¯‚鐸Œ´×–E‚©‚ç‚̐¸ŽqŒ`¬’²ß
̂½‚߂̊튯”|—{Œn‚̍쐬
“¡“c@‘å•ã@@ƒAƒJƒnƒ‰ƒCƒ‚ƒŠ—‘–Œ‚É‚¨‚¯
‚鐸ŽqŒ‹‡—̈æ‚Ì“¯’è‚ÌŽŽ‚Ý
“n•Ó@r•F@@Ä\¬‰–—Þ—n‰t‚ð—p‚¢‚½ƒAƒJƒnƒ‰ƒCƒ‚ƒŠ¸Žq‚̉^“®’²ß‚ÉŠÖ‚·‚錤‹†

 

2000”N
‰Á“¡@D”ü@@ƒƒ_ƒJ—‘‘ƒ‚Ì”­¶‚É‚¨‚¯‚éFGF‚Ì•ª•z‚̕ω»‚͐¶B×–E‚Ì•ª‰»‚Æ“Æ—§‚É‹N‚±‚é
²X–؁@—²L@ƒƒ_ƒJ¸‘ƒ‚É”­Œ»‚·‚éFGF‚̃Qƒmƒ€ˆâ“`Žq‚Ì’P—£‚ÌŽŽ‚Ý
‚‹´@d˜a@@ƒAƒJƒnƒ‰ƒCƒ‚ƒŠƒWƒFƒŠ[‘wŒ`¬‰ß’ö‚É‚¨‚¯‚éŽó¸”\‚ÌŠl“¾‚ÉŠÖ‚·‚錤‹†
H•½@‰xŽq@@ƒAƒJƒnƒ‰ƒCƒ‚ƒŠ—‘–Œ‚É‚¨‚¯‚éZP3ƒ^ƒ“ƒpƒNŽ¿‚̋Ǎ݂Ƃ»‚ÌŒ`¬‰ß’ö‚̉ðÍ

 

2001”N
’å•û@‹vl@@ƒƒ_ƒJ¸ŽqŒ`¬‚̐is‚Ì—}§‚É‚¨‚¯‚鐶B×–E-‘̍זEŠÔ‚Ì‘ŠŒÝì—p‚ÉŠÖ‚·‚錤‹†
“ú‹g@Â@@@ƒŒƒNƒ`ƒ“‚ð—p‚¢‚½ƒCƒ‚ƒŠ¸Žq‚̐æ‘Ì”½‰ž—U‹N‚ÉŠÖ—^‚·‚镪Žq‚Ì’Tõ
’†‘ò@—m”ü@@ƒAƒJƒnƒ‰ƒCƒ‚
Š‚̎󐸂ɂ¨‚¯‚é—‘ƒWƒFƒŠ[‘w‚Ìw\‘¢‚Ì–ðŠ„‚ÉŠÖ‚·‚錤‹†

 

2002”N
ó–ì@½@@@ƒ}ƒCƒNƒƒCƒ“ƒWƒFƒNƒVƒ‡ƒ“–@‚ð—p‚¢‚½ƒCƒ‚ƒŠ—‘•ê×–E‚ւ̈â“`Žq“±“üŒn‚ÌŠm—§
Šâè@—TŽq@@ƒƒ_ƒJ¸‘ƒŠíŠ¯”|—{Œn‚ð—p‚¢‚½¸ŽqŒ`¬‚Ì‹Gß•Ï‰»‚ÉŠÖ‚·‚錤‹†
•ž•”@—zˆê@@Estradiol17-ƒÀ‚ðŒoŒû“Š—^‚µ‚½ƒƒ_ƒJ‚ª¸ŽqŒ`¬‚Ì’²ß‚Ɏ󂯂é‰e‹¿

 

2003”N
”‘q@Žj@@ƒŒƒNƒ`ƒ“‚ð—p‚¢‚½ƒCƒ‚ƒŠ—A—‘ŠÇ•ª”å×–E‚̐õF«‚Ì‘Šˆá‚ÉŠÖ‚·‚錤‹†@
“ê“c@‹Å@@@ƒƒ_ƒJ¸‘ƒ‚Å”­Œ»‚·‚ésplicing factor‚ÌŒ¤‹†

 

2004”N
¡ˆä@^—Žq@”|—{Œn‚ð—p‚¢‚½ƒƒ_ƒJ¸ŽqŒ`¬‚Æ‚»‚Ì’²ß‹@\@
@@@@@@@-‰ßd—͊‹«‚ª¸ŽqŒ`¬‚É‹y‚Ú‚·‰e‹¿‚ÉŠÖ‚·‚錤‹†-
’|“‡@LÆ@@ƒCƒ‚ƒŠŽq‹{‚Å”r—‘Žž‚É”­Œ»‚·‚éˆâ“`Žq‚̃Tƒuƒgƒ‰ƒNƒVƒ‡ƒ“–@‚ð
—p‚¢‚½‰ðÍ
•Ÿ•x@ŒhŽq@@ƒCƒ‚ƒŠ¸Žqæ‘Ì”½‰ž—U‹NˆöŽq‚É“ÁˆÙ“I‚É”½‰ž‚·‚郂ƒmƒNƒ[ƒiƒ‹R‘̍쐬‚ÌŽŽ‚Ý

 

2005”N
rì@‘@@@degenerate primer‚ð—p‚¢‚½ƒƒ_ƒJneuroD/neurogenin class bHLHˆâ“`Žq‚Ì’Tõ
ˆÉ“¡@b—Y@@ƒƒ_ƒJ¸‘ƒŠíŠ¯”|—{Œn‚ð—p‚¢‚½17ƒ¿,20ƒÀ-dihydroxy-4pregnen-3one‚̐¸ŽqŒ`¬‚ɑ΂·‚éì—p‚̉ðÍ
‰ª‘º@—mŽq@@Xenopus tropicalis—‘ƒWƒFƒŠ[‘w‚ÉŠÜ‚Ü‚ê‚é“œ½‚̋ǍÝ
ŒÃì@‰€Ž}@@ƒˆƒRƒXƒWƒJƒWƒJiHemilepidotus gilbertij‘æˆê¸•ê×–E‚©‚ç‚Ì“ñŒ^¸Žq•ª‰»—lŽ®‚ÉŠÖ‚·‚錤‹†

 

2006”N
X@N”Ž@@@
17ƒ¿,20ƒÀ-dihydroxy-4pregnen-3one‚̓ƒ_ƒJ‚Ì•ª‰»Œ^AŒ^¸Œ´× –E‚Ì‘B‚𑣐i‚·‚é
‹g‰ª@‹MŽu@@ƒƒ_ƒJ(Oryzias latipes) ×–E”|—{ðŒ‰º‚̐¸Žq‚ÆŠC…“K‰žƒƒ_ƒJ‚̐¸Žq‚̉^“®‰ðÍ
—Ž‡@Ll@@ŠeŽí‘jŠQÜ‚ð—p‚¢‚½ƒAƒJƒnƒ‰ƒCƒ‚ƒŠ¸Žqæ‘Ì”½‰ž‚̍זE“àM†“`’BŒn‚̉ðÍ

 

2007”N
“ú–ì@–¾‹IØ@ƒCƒ‚ƒŠæ‘Ì”½‰ž—U‹N•¨Ž¿‚ÌN––’[ƒAƒ~ƒmŽ_”z—ñ‚̉ð“Ç‹y‚Ñ“d‹C‰j“®‚É‚æ‚é’P—£–@‚ÌŒŸ“¢

 

2008”N
‘¾“c@^“Þ”ü@ƒgƒEƒzƒNƒTƒ“ƒVƒ‡ƒEƒEƒIiHynobius lichenatusj—‘ƒWƒFƒŠ[‘w’†‚̐¸Žq‰^“®ŠJŽnˆöŽq‚̖ƉuŠw“I “¯’è
’†ì@^ŽÀ@@ƒAƒJƒnƒ‰ƒCƒ‚ƒŠ—‘ƒWƒFƒŠ[‘w‚É‚¨‚¯‚鐸Žqæ‘Ì”½‰ž—U‹NˆöŽq‹y‚щ^“®ŠJŽnˆöŽq‚̋ǍݗlŽ®

–x]@‰Â“ÞŽq@DMC‚Pˆâ“`Žq”­Œ»‚ðŽw•W‚Æ‚µ‚½ƒƒ_ƒJ¸‘ƒ‚É‚¨‚¯‚é ¸ŽqŒ`¬Šˆ«•]‰¿ŒnŠm—§‚ÌŽŽ‚Ý

 

2009”N
’J–ì@r•½@@ƒAƒJƒnƒ‰ƒCƒ‚ƒŠ—A¸ŠÇ“à‚É‚¨‚¯‚é’™‘ ¸Žq‚̎󐸔\ˆÛ Ž‹@\‚̉ðÍ
Œj@—m•½@@@NMDAŽó—e‘Ì‚ð‰î‚µ‚½ƒAƒJƒnƒ‰ƒCƒ‚ƒŠ¸Žq‚ÌŽ©”­“I‰^“®ŠJŽn‚Ì—}§
ŒB‘ò@Œb
@@@ƒAƒJƒnƒ‰ƒCƒ‚ƒŠ¸Žq‰^“®ŠJŽnˆöŽqˆâ“`Žq‚Ì’Tõ
²–ì@›‰@@@ƒCƒ‚ƒŠ—‘ƒWƒFƒŠ[‘wÅŠO‘w‚̃V[ƒgó\‘¢‚Ì•ö‰ó‚ÉŠÖ—^‚·‚éƒ^ƒ“ƒpƒNŽ¿•ª‰ðy‘f‚ÉŠÖ‚·‚錤‹†

 

2010”N
r–؁@rK@@ƒAƒJƒnƒ‰ƒCƒ‚ƒŠ¸Žq‚̃ZƒŠƒ“ƒvƒƒeƒA[ƒ[Šˆ«‚͎󐸎ž‚̉^“®ŠJŽn‚É•K{‚Å‚ ‚é
¬¼@³®@@ƒAƒJƒnƒ‰ƒCƒ‚ƒŠ‚É‚¨‚¯‚鐸Žq×–E“àƒJƒ‹ƒVƒEƒ€ƒŒƒxƒ‹ˆÛŽ‹@\‚ÉŠÖ‚·‚錤‹†

 

2011”N
ŽÄ“c@”¿˜Q@ @ƒCƒ‚ƒŠ¸Žq‰^“®ŠJŽnˆöŽq‚ÌŠˆ«‰»‚ÉŠÖ‚·‚é“dŽqŒ°”÷‹¾Šw“IŒ¤‹†
–L“c@«@@@ƒTƒUƒ“ƒuƒƒbƒeƒBƒ“ƒO‚É‚æ‚éƒCƒ‚ƒŠ¸Žq‰^“®ŠJŽnˆöŽq‚̈â“`Žq‚̉ðÍ

 

2012 ”N
²“¡@çØ”ü@SOD1KOƒ}ƒEƒXA‹y‚ÑALRKOƒ}ƒEƒX‚É‚¨‚¯‚鐸Žq‰^“®‚Ì’´Šˆ«‰»ƒp
ƒ^[ƒ“‚̉ðÍ
‚‹´@’qŒb@@ƒCƒ‚ƒŠ¸Žq‚Ì’´Šˆ«‰»‚³‚ꂽ‰^“®‚É‚¨‚¯‚é×–E“àCa2+‚ƃAƒfƒjƒ‹Ž_ƒVƒNƒ‰[ƒ[‚Ì–ðŠ„
“¡“c@K—C@@ƒAƒJƒnƒ‰ƒCƒ‚ƒŠ¸Žq‰^“®ŠJŽnˆöŽq‚̈â“`Žq”­Œ»‚̉ðÍ
‰¡]@”ü—¢@@ƒAƒJƒnƒ‰ƒCƒ‚ƒŠ¸ŽqƒvƒƒeƒA[ƒ[Šˆ«‚̋Ǎ݂Ǝ󐸂ɂ¨‚¯‚é–ðŠ„

 

2013”N
—L‘º@Œ’Žu@ Motility analysis of the sperm produced by aldehyde reductase-KO mice
Ö“¡@àôŽq@@Effect of SMIS peptides on the motility of amphibian sperm under a hyposmotic condition.
‚‹v@²˜N@@4|ƒAƒ~ƒmƒsƒŠƒWƒ“‚É‚æ‚Á‚Ĉø‚«‹N‚±‚³‚ê‚éƒAƒJƒnƒ‰ƒCƒ‚ƒŠ¸Žq‰^“®‚̉ðÍ

 

2014”N
‹yì@T”V‰î@   RNAseq‚ð—p‚¢‚½ƒAƒJƒnƒ‰ƒCƒ‚ƒŠ¸×–E‚Å”­Œ»‚·‚éƒAƒfƒjƒ‹Ž_ƒVƒNƒ‰[ƒ[ˆâ“`Žq‚Ì“¯’è
”ª–؏À@Œcˆê˜Y   RNAseq‚ð—p‚¢‚½ƒAƒJƒnƒ‰ƒCƒ‚ƒŠ¸×–E‚Å”­Œ»‚·‚é“dˆÊˆË‘¶«Ca2+ƒ`ƒƒƒlƒ‹ˆâ“`Žq‚Ì“¯’è

 

2015”N

ˆäã@OÍ@@ƒAƒJƒnƒ‰ƒCƒ‚ƒŠƒWƒFƒŠ[‘w\¬•¨Ž¿‚Ì‘¶Ý‰º‚É‚¨‚¯‚鐸Žqƒ^ƒ“ƒpƒNŽ¿ƒŠƒ“Ž_‰»ƒpƒ^[ƒ“‚̉ðÍ

‹ß@a”V‰î@@ƒAƒJƒnƒ‰ƒCƒ‚ƒŠ¸Žqæ‘Ì”½‰ž‚ɑ΂·‚écAMP‚̍ì—p

•½–ì@‚‘å@@ƒQƒmƒ€•ÒW‚É‚æ‚éƒAƒJƒnƒ‰ƒCƒ‚ƒŠƒ`ƒƒVƒi[ƒ[ˆâ“`ŽqƒmƒbƒNƒAƒEƒg

…ŒË@T–ç@@ƒAƒJƒnƒ‰ƒCƒ‚ƒŠSMISˆâ“`Žq‚̃Qƒmƒ€\‘¢

 

2016”N

ì‘º@^ˆŸŽq@—¼¶—ސ¸Žq‰^“®’²ß‹@\‚ÌŽí“ÁˆÙ«‚Í2Ží—Þ‚ÌTŒ^“dˆÊˆË‘¶«Ca2+ƒ`ƒƒƒlƒ‹‚ð‰î‚µ‚Ä•t—^‚³‚ê‚é

 

2018 ”N

‰““¡@‘å‰î@ˆâ“`“I‚ɋψê‚ȃAƒJƒnƒ‰ƒCƒ‚ƒŠŒÂ‘ÌŠÔ‚É‚¨‚¯‚鐸Žq‚ÌŽ©”­“Iæ‘Ì”½‰ž”\‚Ì‘Šˆá

â¼@D@ƒAƒJƒnƒ‰ƒCƒ‚ƒŠ’™‘ ¸Žq‚É‚¨‚¯‚é×–E“àCa2+‚̋Ǎ݈ێ‹@\‚ÉŠÖ‚·‚錤‹†

¬濵@q@@ƒ[ƒmƒpƒX¸Žq‚É‘¶Ý‚·‚éCa2+“§‰ß«ƒ`ƒƒƒlƒ‹‚Ì’Tõ

 

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